Work

Mild Aerobic Oxidation of Secondary Alcohols with Water Tolerant Cu(I) Catalyst

Year: 2024

Type: article

Abstract: Green, aerobic oxidation of secondary alcohols to ketones poses a significant synthetic challenge. To address this, we have developed a highly active (DPA)CuI/ABNO catalyst system capable of aerobically oxidizing a wide range of secondary alcohols, including benzylic and aliphatic derivatives, yielding the corresponding ketones with high yields. The unique feature of this Cu(I) catalyst is its high stability, even in the presence of water. We also prepared CuI from waste copper sources to enhance the system's sustainability.

Source: ChemSusChem

DOI: 10.1002/cssc.202402236

Authors: Faranak Heshmatnia, Anže Zupanc, Aleksi Eronen, Emi Lagerspets, Joseph Install, Timo Repo

Institutions: University of Helsinki, Aalto University, University of Ljubljana

Language: English

Topic: Oxidative Organic Chemistry Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,330

Funders: Helsingin Yliopisto, Magnus Ehrnroothin Säätiö