Work

Analysis of risk factors related to acute exacerbation in patients with chronic pancreatitis: a retrospective study of 313 cases from a single center in China

Year: 2024

Type: article

Abstract: BACKGROUND: Acute on chronic pancreatitis(ACP) is a common cause of treatment in patients with chronic pancreatitis(CP). However, as far as we know, research on ACP has been few, and the quality may vary. This study intended to explore the risk factors related to acute exacerbation in patients with chronic pancreatitis. METHODS: 313 patients with CP were analyzed based on clinical data from 2014 to 2023 and categorized into ACP and non-ACP groups. Their data, assessed across eleven parameters, were used to study risk variables associated with acute exacerbation in patients with chronic pancreatitis. RESULTS: Of the 313 eligible patients, 163(52.1%) were ACP. Age > 50 years old (P = 0.049, OR = 0.614, 95%CI: 0.378-0.998), recurrent acute pancreatitis(RAP) history (P = 0.000, OR = 3.284, 95%CI: 1.972-5.467) and steatorrhea (P = 0.013, OR = 0.189, 95%CI: 0.051-0.704) were related factors for ACP. CONCLUSION: The history of RAP was an independent risk factor for ACP. Age and steatosis were protective of the prevalence of ACP.

Source: BMC Gastroenterology

DOI: 10.1186/s12876-024-03528-w

Authors: Jiaming Liu, Cong Wang, Zhen Chen, Qili Dai, Jingrui Bai, Yun‑Feng Cui

Institutions: Tianjin Medical University, Tianjin Nankai Hospital

Language: English

Topic: Pancreatitis Pathology and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990