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Discovery of novel hybrid tryptamine-rivastigmine molecules as potent AChE and BChE inhibitors exhibiting multifunctional properties for the management of Alzheimer's disease

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Year: 2024
Type: article
Source: European Journal of Medicinal Chemistry
DOI: 10.1016/j.ejmech.2024.117066
Authors: Gauri Shankar, Prabhat Kumar, Sanskriti Rai, Aparajita Ghosh, Tanmaykumar Varma, Mushtaq Ahmad Wani, Sunil Kumar, Upesh Mandloi, Gireesh Kumar Singh, Prabha Garg, Onkar Kulkarni, Saripella Srikrishna, Saroj Kumar, Gyan Modi
Institutions: Indian Institute of Technology BHU, Banaras Hindu University, All India Institute of Medical Sciences, Birla Institute of Technology and Science - Hyderabad Campus, Birla Institute of Technology and Science, Pilani, National Institute of Pharmaceutical Education and Research, National Institute of Pharmaceutical Education and Research, Luleå University of Technology, Central University of South Bihar
Language: English

Topic: Cholinesterase and Neurodegenerative Diseases
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Indian Council of Medical Research, Banaras Hindu University, Science and Engineering Research Board
Awards: G8446132947, G8827244263, G9000135497
OpenAlex ID: W4404763305
FWCI: 5.393
Cites: 67
Cited by: 23
Related to: 10
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