Work

Coronary Artery Ectasia in Acute Coronary Syndrome: The Role of Non-vitamin K Antagonist Oral Anticoagulants in Management

Year: 2024

Type: article

Abstract: Coronary artery ectasia (CAE) is an abnormal dilatation of coronary artery segments, often linked with atherosclerosis. This report discusses two cases of CAE presenting as acute coronary syndrome. A 36-year-old man had proximal blockage in the left circumflex artery (LCx) and ectasia in the obtuse marginal artery and left anterior descending artery (LAD), while a 53-year-old male smoker had an ectatic LAD with a substantial thrombus. Both were treated with dual antiplatelet therapy (aspirin and clopidogrel) and non-vitamin K antagonist oral anticoagulants (NOACs), specifically apixaban, along with atorvastatin. The first patient had complete resolution of LCx occlusion after 1 year, and the second patient had complete thrombus dissolution in the LAD in 2 months. These cases highlight the potential benefits of NOACs in managing CAE in acute coronary syndrome, suggesting that triple therapy can significantly improve clinical outcomes.

Source: Interventional Cardiology Reviews Research Resources

DOI: 10.15420/icr.2024.25

Authors: Mahmoud Izraiq, Nail Alshoubaki, Omran A Abu-Dhaim, Sarah Al-Qalalweh, Raed Aqel

Institutions: Specialty Hospital, Jordan, Jordan University Hospital

Language: English

Topic: Antiplatelet Therapy and Cardiovascular Diseases

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,146