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An evidence-based nursing practice affects stress state, coagulation, complications and quality of life in patients with upper gastrointestinal bleeding in the emergency department: a retrospective observational study

Year: 2024

Type: article

Abstract: BACKGROUND: Acute gastrointestinal bleeding (GIB) is a common surgical emergency digestive system disorder with high morbidity and mortality. AIM: This study sought to explore effects of evidence-based nursing practice (ENP) procedures on stress state, coagulation function, complications in patients with upper GIB (UGIB) and quantify of life in emergency department. METHODS: This study was a retrospective analysis and a total of 120 patients with UGIB were enrolled and divided into an experimental group with ENP interventions and a reference group with traditional nursing according to different nursing programs. The physiological stress indicators (epinephrine, norepinephrine, plasma cortisol), psychological stress indicators [anxiety self-assessment scale (SAS), depression self-assessment scale (SDS)], coagulation function indicators [prothrombin time (PT), prothrombin time (TT), D-dimer (D-D), fibrinogen (FIB)], complication rate and quality of life were analyzed. RESULTS: After nursing intervention, epinephrine, norepinephrine and plasma cortisol, SDS and SAS scores were decreased in the experimental group relative to the reference group (all P < 0.001). After nursing intervention, the levels of PT, TT and D-D in both groups were lower and the FIB was higher than before intervention (all P < 0.001), and the improvement of coagulation function indexes in experimental group after nursing was better than that in reference group (P < 0.001). The incidence of complications in the experimental group was lower than that in the reference group (P = 0.04). The higher quality of life scores after nursing intervention was validated in the experimental group relative to the reference group (P < 0.001). CONCLUSION: ENP improved stress response, coagulation function, quality of life, and reduced incidence of complications in UGIB patients, indicating potential for clinical application.

Source: BMC Gastroenterology

DOI: 10.1186/s12876-024-03507-1

Authors: Juan Hu, Chengli Zhou, Ling Feng, YuHong Yang

Institutions: Southwest Medical University, Affiliated Hospital of Southwest Medical University

Language: English

Topic: Gastrointestinal Bleeding Diagnosis and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990