Comparative Effectiveness and Safety of Immune Checkpoint Inhibitors in Patients with Hepatocellular Carcinoma Based on Viral Etiology
Year: 2024
Type: article
Abstract: Background : Immune checkpoint inhibitors (ICI) are antitumor agents employed in the treatment of hepatocellular carcinoma (HCC), which enhance T-cell function by targeting immune escape pathways.HCC is classified into viral and non-viral types based on its etiology, with the viral form often linked to an immunosuppressive microenvironment due to T-cell tolerance.However, existing research on how viral etiology influences ICI therapy outcomes is limited.This study evaluated the efficacy and safety of ICI in viral versus non-viral HCC in a Korean population.이재연 : 간세포암 환자에서 바이러스 병인에 따른면역관문억제제의 효과 및 안전성 비교 간암은 전세계적으로 높은 유병률을 보이며,
Authors: Jae Yeon Lee, Min Jung Geum, Jong Hee Ko, Eun Sun Son, Yun Mi Yu
Institutions: Yonsei University, Severance Hospital
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404771843