Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome
Year: 2024
Type: article
Study design: Case Report
Abstract: We report on a previously non-HIV-diagnosed, 47-year-old male diagnosed with diabetes mellitus (DM) and cryptococcal meningoencephalitis, who was referred to our institution for antifungal treatment. During the course of treatment, due to the development of refractory intracranial hypertension, Ommaya reservoirs were employed for cranial pressure reduction. The patient gradually recovered during subsequent antifungal therapy; however, symptoms worsened in the third month of treatment, leading to consideration of post-infectious inflammatory response syndrome (PIIRS) on examination. Once diagnosed, the symptoms improved significantly after approximately 130 days of treatment with additional corticosteroids.
Source: Frontiers in Immunology
Authors: Qinghua Chen, Weitong Yu, Xuyi Wang, Chenxi Zhao, Pin Wang, Lin Sun, Linlin Xu, Yingying Xu
Institutions: Shandong University, Second Hospital of Shandong University
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,295
Award: G4751526745
OpenAlex ID: W4404773865