Identification of Cadmium (CD) metal binding sites in _Eudrilus eugeniae using Insilico protocols
Year: 2024
Type: article
Abstract: The application of Eudrilus eugeniae earthworm species in bioremediation of contaminated soil results in a decrease in the concentration of pollutants by way of a mechanism known as bioaccumulation.Eudrilus eugeniae's body accumulation of cadmium metal is the subject of the current insilico study.The Cytochrome Oxidase 1 (COX1) protein of Eudrilus eugeniae accumulates cadmium metal.This study's technique includes molecular drug docking and H-bond interaction research using sophisticated automated drug docking platforms.The findings unequivocally demonstrate that Eudrilus eugeniae contains a significant amount of cysteine residues, which bind to a variety of heavy metals, most notably cadmium.Our findings align with the previously validated wet lab results as well.Ultimately, it was determined that cadmium metal directly binds to cysteine-rich amino acid locations.Based on the expression of the Cytochrome Oxidase 1 protein, these results have demonstrated that Eudrilus eugeniae is capable of collecting Chromium metal in its body.The complete Insilico study describes in detail how metals build up in a specific species of earthworm.
Author: Suvedha A
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4404776917