Work

Cinnamaldehyde release behavior of Pickering emulsion synergistically stabilized by Sapindus mukorossi modified palygorskite and chitosan

Year: 2024

Type: article

Abstract: • Green Pickering emulsion was designed for controllable release of CIN. • Pickering emulsion was co-stabilized by Sm modified Pal and CS. • CS and CIN took place interfacial cross-linking at the oil-water interface. • Controlled release of CIN was determined with CS amount and emulsion stability. • The growth of E. coli and S. aureus was almost suppressed after adding 25 µL/mL Pickering emulsion. Most of the studies are committed to explore the natural green stabilizer or bio-stabilizer to design biocompatible Pickering emulsion, while few works focus on developing a dynamic interfacial regulatory effect for the slow-release of active molecules from Pickering emulsion. Herein, Pickering emulsion was fabricated for the controlled release of cinnamaldehyde, which was synergistically stabilized by palygorskite modified with the active ingredients leached from Sapindus mukorossi and chitosan. The results showed that the interfacial cross-linking between chitosan and cinnamaldehyde took place at the oil-water interface based on the formation of Schiff base, while the modified palygorskite was adsorbed onto the oil-water interface to co-stabilize Pickering emulsion. The simulated gastrointestinal experiment indicated that the emulsion was stable in simulated gastric fluid (SGF) of pH 1.5, and then destroyed in simulated intestinal fluid (SIF) of pH 6.8 to realize the continuous release of cinnamaldehyde, where the amount of chitosan played a vital role. Furthermore, the antibacterial test showed that the growth of Escherichia coli and Staphylococcus aureus was almost completely suppressed when the concentration of Pickering emulsion was 25 µL/mL. Therefore, this study developed a facile strategy to regulate the controlled release of cinnamaldehyde based on green Pickering emulsion.

Source: Carbohydrate Polymer Technologies and Applications

DOI: 10.1016/j.carpta.2024.100614

Authors: Aiping Hui, Bin Mu, Yongfeng Zhu, Peng Liu, Aiqin Wang

Institutions: Chinese Academy of Sciences, Lanzhou Institute of Chemical Physics, State Key Laboratory of Applied Organic Chemistry, Lanzhou University

Language: English

Topic: Pickering emulsions and particle stabilization

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,210

Funders: National Natural Science Foundation of China, Natural Science Foundation of Gansu Province