Work

INCA033989: the first shot on goal for MPNs?

Year: 2024

Type: article

Abstract: ABSTRACT: In this issue of Blood, Reis et al1 identify a monoclonal antibody, INCA033989, that selectively targets mutant calreticulin (mutCALR) in myeloproliferative neoplasms (MPNs), inhibiting its oncogenic activity without affecting normal hematopoiesis.

Source: Blood

DOI: 10.1182/blood.2024026811

Authors: Camelia Benlabiod, Bethan Psaila

Institutions: University of Oxford, Oxford University Hospitals NHS Trust

Language: English

Topic: Myeloproliferative Neoplasms: Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4404815641