Work

3-Methyl-2-(5-((trimethylsilyl)ethynyl)pyridin-2-yl)butan-2-ol

Year: 2024

Type: article

Abstract: The reactions of dialkylzinc reagents with ketones are scarcely studied. In this paper, we describe a previously unknown direct alkylation of substituted 2-acetylpyridine with diisopropyl zinc, which gave a corresponding novel alcohol with 82% yield.

Source: Molbank

DOI: 10.3390/m1925

Authors: Oleg A. Mikhailov, Almira R. Kurbangalieva, Ilya D. Gridnev

Institutions: N.D. Zelinsky Institute of Organic Chemistry, Kazan Federal University

Language: English

Topic: Coordination Chemistry and Organometallics

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $568

Funder: Russian Science Foundation