Work

Experience With the Use of Paromomycin Via Nasogastric Tube as Treatment for Cryptosporidium Infection: A Case Report

Year: 2024

Type: article

Abstract: Cryptosporidiosis is an infectious disease caused by the Cryptosporidium parasite, primarily affecting the gastrointestinal tract of both humans and animals. Transmission occurs via fecal-oral route, mainly through ingestion of water or food contaminated with oocysts, the parasite's infectious form. Immunocompromised individuals are particularly susceptible to severe and prolonged symptoms. Current treatment strategies involve supportive measures and antiparasitic medications such as nitazoxanide and paromomycin, although patients with predisposing factors have an elevated risk of recurrence. There is currently no evidence supporting the use of paromomycin via nasogastric tube. Therefore, we present our experience with the use of an extemporaneous paromomycin solution and its clinical impact.

Source: Hospital Pharmacy

DOI: 10.1177/00185787241299621

Authors: Iván Cores Rodríguez, Eduardo Tejedor Tejada, Daniel Ortiz del Olmo, Marta Bernárdez Domínguez, Maria Teresa Criado Illana

Institutions: Hospital General De Segovia, Hospital Universitario Río Hortega

Language: English

Topic: Parasitic Infections and Diagnostics

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4404829668