Work

The Relationship Between Preoperative Vitamin D Levels and Keloid Recurrence

Year: 2024

Type: article

Abstract: ABSTRACT Background Keloids, characterized by excessive collagen deposition, often recur despite various treatments. This study explores the association between preoperative serum vitamin D levels and keloid recurrence in a Korean population. Methods A retrospective cohort of 160 patients who underwent keloid excision was analyzed. Preoperative serum 25(OH) vitamin D and 1,25(OH) 2 vitamin D levels were measured. Recurrence rates were compared using hierarchical logistic regression, adjusting for potential confounders. Results Age was significantly associated with keloid recurrence (OR: 0.934, p = 0.009), indicating older age was linked to lower recurrence risk. No significant association was found between preoperative 25(OH) vitamin D ( p = 0.395) and 1,25(OH) 2 vitamin D levels ( p = 0.925) and keloid recurrence. Conclusions Preoperative vitamin D levels do not predict keloid recurrence in this Korean cohort, while age is a significant predictor. Understanding the multifactorial nature of keloid pathogenesis requires further investigation into other potential risk factors.

Source: Journal of Cosmetic Dermatology

DOI: 10.1111/jocd.16687

Authors: Da Woon Lee, Daihun Kang, Boram Ha, Da Hye Kim, Choong Hyun Chang, Tae Hwan Park

Institutions: Soonchunhyang University, Ewha Womans University Seoul Hospital, Hallym University, Hallym University Dongtan Sacred Heart Hospital

Language: English

Topic: Dermatologic Treatments and Research

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,500