Work

The Role of Neurodegeneration in Depression: Inflammatory Responses and Treatment Options

Year: 2024

Type: article

Abstract: Neurodegeneration has emerged as a significant factor contributing to depression, a prevalent mental health disorder affecting millions worldwide. This article reviews the interplay between neurodegenerative processes and depression, focusing on inflammatory responses that exacerbate this relationship. Evidence suggests that neuroinflammation is a critical mediator in the pathophysiology of depression, linking cognitive decline with mood disturbances. Furthermore, this review discusses various treatment options, including pharmacological and non-pharmacological approaches, emphasizing the importance of addressing underlying neurodegenerative mechanisms to optimize therapeutic outcomes.

Source: Universal library of medical and health sciences.

DOI: 10.70315/uloap.ulmhs.2024.0204003

Author: Kian Zehtabian

Institution: Islamic Azad University South Tehran Branch

Language: English

Topic: Tryptophan and brain disorders

Subfield: Biological Psychiatry

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Islamic Azad University