Long COVID symptoms 6 months after acute infection among people living with HIV and people not living with HIV
Year: 2024
Type: article
Study design: Observational Study
Abstract: Background: Chronic viral infections, such as Human Immunodeficiency Virus (HIV), and their reactivation are considered potential contributing factors to Long-Corona Virus Disease (LC). However, research on the long-term sequelae of Long-COVID in individuals with HIV is limited. Methods: We conducted a case-control study involving a total of 84 participants categorized into two groups: people living with HIV (PLWH) and people not living with HIV (PNLWH) within the six-month post-infection LC population. Differences in sequelae symptoms, cardiovascular biomarkers (VCAM-1, ICAM-1, and ACE2), Severe Acute Respiratory Syndrome Coronavirus 2 neutralization antibodies (SARS-CoV-2 nAb) and cytokines (IFN-γ, IL-6, and IL-17) were analyzed between the two groups. Results: > 0.05, respectively). Conclusion: PLWH had lower symptoms of LC and reduced frequency of symptoms, increased cardiovascular risk factors, and no differences in levels of inflammation or SARS-CoV-2 nAb levels when compared to PNLWH.
Source: Frontiers in Immunology
Authors: Qin Li, Yijie Ma, Peng He, Dongqiong Chen, Tingrui Zhang, Xiaoying Wang, Ying Xu, Peiming Li, Weibo Wen, Zefeng Wang
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,295
Awards: G2826603151, G8855894865
OpenAlex ID: W4404832606