Year: 2024
Type: other
Abstract: This chapter discusses a variety of minor antimicrobial classes used in veterinary medicine– the ionophores, nitrofurans, nitroimidazoles, and rifamycins, in detail. It briefly comments on other antimicrobials, including oxazolidinones, carbadox, fusidic acid, isoniazid, mupirocin, methenamine, and novobiocin. The dose necessary to cause toxicity is variable among species, with equine species being the most sensitive and turkeys being more sensitive than chickens. It includes lasalocid, maduramicin, monensin, naracin, salinomycin and semduramicin. Because of carcinogenicity, the nitrofuransare of high regulatory concern in many countries. Nitroimidazoles are heterocyclic compounds based on a five-membered nucleus similar to that of the nitrofurans. The oxazolidinones are a novel chemical class of synthetic antimicrobials. Fusidic acid is used orally in humans in some countries for the treatment of serious staphylococcal infections. The main use of novobiocin in veterinary medicine is in the local treatment of S. aureus mastitis in dairy cows.
Authors: Patricia M. Dowling, Keith E. Baptiste
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4404846820