Assessment of the Migration/Invasion Traits of Acquired Resistant BT 549 Gem100nM Breast Cancer Cell Lines
Year: 2024
Type: article
Abstract: One of a cell's behavioural characteristics is migration. Cell migration is a major contributor to cancer-related mortality and plays a significant role in the spread of metastatic tumours. The purpose of this study was to evaluate the invasive characteristics and migration traits of acquired gemcitabine-resistant BT 549 Gem100nM breast cancer cell lines. According to data from the results obtained, the resistant cell lines Clones 1 and 4 exhibited higher migratory and invasive activities than the wild-type cell line BT549. This suggests that acquired resistance may cause cancer cells to become more lethal by increasing their migratory and invasive characteristics.
Author: Tawari, E. P.
Language: English
Topic: Cancer Cells and Metastasis
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4404851403