Prognostic Factors in 26 Cats Undergoing Surgery for Extra-Hepatic Biliary Obstruction
Year: 2024
Type: article
Abstract: Surgical management of feline extra-hepatic biliary obstruction (EHBO) has poor survival rates with few prognostic factors reported in the literature. The etiology and clinical findings of feline EHBO and their influence on short-(2 weeks-6 months) and long-term (>6 months) survival and prognosis were examined in an observational clinical retrospective study of 26 client-owned cats undergoing surgery for biliary obstruction at one institution between 2012 and 2020. The etiology of EHBO was determined in 21/26 cats, which included inflammatory causes (14/21), neoplastic causes (6/21), and a duodenal foreign body (1/21). Pre-operative hyperbilirubinemia and post-extubation hypotension (mean arterial pressure < 60 mmHg) were statistically associated with reduced short- and long-term survival. Short-term survival was documented in 17/26 cats, and long-term survival in 13/26 cats. Median survival time (MST) was 86 days (range, 0-1497). An MST of 17 days (range, 2-520) in cats with malignancies was found compared to an MST of 1165 days (range, 61-2268) in EHBO resulting from inflammatory complexes. Pre-operative hyperbilirubinemia and immediate post-operative hypotension may represent prognostic factors for cats undergoing surgery for EHBO. Cats with inflammatory causes of EHBO carry a more favorable prognosis than neoplastic causes. Further studies are required to evaluate the validity of the observed associations.
Source: Veterinary Sciences
Authors: Jonathan P. Speelman, Ki-Lam Hui, Nicolas T. Woodbridge, Susanne Pfeiffer, Julia A. Beatty, Alan H. Taylor
Institution: City University of Hong Kong
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,955
OpenAlex ID: W4404854580