Work

Near Infrared Photoimmunotherapy for Locoregionally Recurrent Oropharyngeal Squamous Cell Carcinoma at Tongue Base After Chemoradiotherapy: A Case Report and Literature Review

Year: 2024

Type: article

Abstract: Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed treatment. We report a successful case of NIR-PIT for post-irradiation locoregionally recurrent oropharyngeal cancer at the tongue base. A 60-year-old man following primary treatment for oropharyngeal cancer at the tongue base by endoscopy (rT1N0M0). He had been treated by concurrent chemoradiotherapy. NIR-PIT was performed under general anesthesia at the tongue base. Successful therapeutic effects were obtained with no postoperative functional impairment. This case report highlights two important management issues: tracheostomy and pain management after NIR-PIT. NIR-PIT for head and neck cancer will provide a curative treatment option for the locoregional recurrent or unresectable disease following radiotherapy and surgery. It was considered important to ensure sufficient optical tissue penetration range, control pain in the perioperative period, and take measures to prevent edema in the airway.

Source: Cureus

DOI: 10.7759/cureus.74742

Authors: Shunji Tamagawa, Katsuya Okuda, Daisuke Nishikawa, Masamitsu Kono, Muneki Hotomi

Institutions: Wakayama Medical University, Aichi Cancer Center

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404855320