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Recurrent Jaundice Unraveled: A Case of Benign Recurrent Intrahepatic Cholestasis (BRIC) in an Indian Patient

Year: 2024

Type: article

Abstract: Benign recurrent intrahepatic cholestasis (BRIC) is a rare, autosomal recessive liver disorder characterized by intermittent episodes of cholestasis without progression to chronic liver disease or cirrhosis. Patients experience recurrent jaundice and severe pruritus, significantly impacting their quality of life. This case report presents a 15-year-old boy with a history of recurrent jaundice and pruritus. The patient was successfully managed with ursodeoxycholic acid (UDCA), leading to symptomatic relief and biochemical improvement. BRIC is a rare disorder and should be considered in the differential diagnosis of recurrent cholestasis in adolescents. Early recognition and appropriate treatment can improve patient outcomes and prevent unnecessary investigations.

Source: Cureus

DOI: 10.7759/cureus.74736

Authors: Rachit Bansal, Abhay Patel, Chinmaya Singh, Kiran N C, Sonakshi Saxena

Institutions: Safdarjang Hospital, Vardhman Mahavir Medical College & Safdarjung Hospital

Language: English

Topic: Pediatric Hepatobiliary Diseases and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404856259