Copper‐Catalyzed Regioselective Reaction for Arylselenation of Unprotected Pyrazoles Using Selenium Powder
Year: 2024
Type: article
Abstract: A new and convenient Cu‐catalyzed three‐component reaction of N‐unsubstituted pyrazoles with Se powder and aryl iodides has been established. The protocol presents a broad substrate scope, good functional group tolerance, and high regioselectivity. The utility of this procedure is further established by gram‐scale synthesis as well as the diversified transformations of 4‐organylselanyl‐1 H ‐pyrazoles to useful compounds.
Source: ChemistrySelect
Authors: Xiaoxu Mu, Yi Wu, Yusheng Pu, Jinghua Ruan, Xin Zha, Suo Gao, Bing Wang, Jianta Wang, Lei Tang, Cong Wang
Language: English
Subfield: Toxicology
Domain: Life Sciences
Open Access status: bronze
Awards: G2945580553, G5754615751
OpenAlex ID: W4404856655