Work

Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity

Year: 2024

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: BACKGROUND/OBJECTIVES: Sleep problems are frequently experienced and play an important role in inflammation and disease risk. US Montmorency tart cherries (MTC) improve sleep outcomes in previous studies, but studies in individuals with overweight and obesity are lacking. METHODS: ) were recruited to this randomized controlled, crossover study. MTC capsules (500 mg) or a placebo were taken one hour before bed for 14 days. Sleep outcomes including total sleep time, deep and REM sleep duration, nap duration, and nocturnal sleep duration were assessed using the Zmachine and/or Fitbit Inspire 3. Subjective sleep information on quality and insomnia symptoms was collected using the Pittsburgh Sleep Quality Index, the Sleep Quality Scale, and the Insomnia Severity Index. Markers of inflammation included C-reactive protein, TNF-α, and IL-6, IL-8, IL-10, and IL-17A. RESULTS: > 0.05 for all). CONCLUSIONS: These results suggest studies of individuals with overweight and obesity should test higher doses of MTC than those currently recommended.

Source: Nutrients

DOI: 10.3390/nu16234125