Work

L5 giant cell tumor in 28-year-old female

Year: 2024

Type: article

Abstract: Background: Giant cell tumor of bone (GCTB) is a rare benign tumor that may also exhibit aggressive local behavior. Recurrence of GCTB is common even after complete resection. GCTB typically occurs in long bones, and only 2.7% are found in the spine. Here, a 28-year-old female with a magnetic resonance (MR)-documented L5 lumbar spine GCTB presented with a cauda equina syndrome effectively managed with a decompressive laminectomy/L4-S1 fusion. Case Description: A 28-year-old female presented with a 1-year history of lower extremity pain/paresthesia that had exacerbated over the previous 1 month. When the MR imaging revealed cauda equina compression due to a L5 hypodense lesion, the patient successfully underwent a decompressive laminectomy/L4-S1 fusion. The histopathology examination confirmed the presence of a GCTB. Conclusion: While gross total excision for GCTB is the treatment of choice, for those undergoing only subtotal/partial resections, additional adjuvant therapy may be warranted. Notably, even despite extensive resections, these lesions have a high rate of recurrence.

Source: Surgical Neurology International

DOI: 10.25259/sni_533_2024

Authors: Wisnu Baskoro, Muhammad Fakhri Raiyan Pratama, Early Isnaeni Nur Fauziah, Hanan Anwar Rusidi, Bidari Kameswari

Institutions: Rumah Sakit Umum Pusat Dr. Soeradji Tirtonegoro, Universitas Gadjah Mada

Language: English

Topic: Bone Tumor Diagnosis and Treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4404867515

FWCI:

Cites: 12

Cited by:

Related to: 10