Work

MALDI - TOF MS for the identification of obligate anaerobes and metronidazole susceptibility of anaerobic Gram negative bacilli

Year: 2024

Type: article

Abstract: MALDI-TOF MS, though has facilitated rapid and accurate anaerobe identification, the problem of rising metronidazole resistance amongst the members of Bacteroides fragilis group is cause for concern. In this one-year study period,152 anaerobic Gram negative bacilli and 60 Gram positive anaerobes were isolated from 167 samples obtained from clinically suspected anaerobic infections. Bacteroides fragilis accounted for 56 % of the total anaerobic GNB and Peptoniphilus asacchrarolyticus was the most commonly isolated Gram positive cocci. All isolates were identified by the MALDI-TOF MS except one isolate each of Clostridium and Peptostreptococcus. E-test for members of Bacteroides fragilis group, demonstrated 26.8 % metronidazole resistance.

Source: Indian Journal of Medical Microbiology

DOI: 10.1016/j.ijmmb.2024.100767

Authors: Simson D, Dhanalakshmi Gounassegarane, Rakhi Biswas

Institution: Jawaharlal Institute of Post Graduate Medical Education and Research

Language: English

Topic: Bacterial Identification and Susceptibility Testing

Subfield: Clinical Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,070