Antibacterial ent -trachyloban-19-oic acid and other constituents from Croton kinondoensis G.W. Hu, Ngumbau & Q.F. Wang
Year: 2024
Type: article
Abstract: Phytochemical analysis of the twigs and leaves of Croton kinondoensis, endemic to Kenya, yielded known compounds 3-(3′,4′-dimethoxyphenyl)-prop-1-ene (1), 3-(3′,4′-dimethoxyphenyl)-propenal (2), lupeol (3) and ent-trachyloban-19-oic acid (4), and a tentatively new ent-clerodane diterpenoid, crotokinondoenolide (5). ent-Trachyloban-19-oic acid (4) showed good activity against a panel of drug-resistant strains of Staphylococcus aureus and Enterococcus spp with MIC values of 25 µg/mL.
Source: Natural Product Research
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Funder: European Commission
OpenAlex ID: W4404892486