A rare case of isolated nasal tip neurofibroma in an 11-year-old female without neurofibromatosis: A case report
Year: 2024
Type: article
Study design: Case Report
Abstract: INTRODUCTION AND IMPORTANCE: Isolated neurofibromas of the nasal tip are uncommon, particularly in pediatric patients. Neurofibromas are benign tumors that arise from the peripheral nerve sheath and are usually associated with neurofibromatosis type 1 (NF1). Isolated cases present unique challenges due to their location and the importance of cosmetic outcomes. This case highlights the presentation, diagnostic process, and management of a rare nasal tip neurofibroma in an 11-year-old girl. CASE PRESENTATION: An 11-year-old female presented with a gradually enlarging mass on the nasal tip over several months, causing cosmetic concern without pain, bleeding, or obstruction. Clinical examination revealed a firm, non-tender lesion, about 1 cm in diameter, with normal skin. Imaging confirmed a well-defined mass localized to the nasal tip. Surgical excision was performed, and histopathology confirmed a diagnosis of neurofibroma. Follow-up showed no recurrence, and the patient was satisfied with the cosmetic result. CLINICAL DISCUSSION: Neurofibromas, though benign, can cause aesthetic concerns, particularly in prominent areas like the nasal tip. Isolated neurofibromas in children without NF1 are rare. Surgical excision is the treatment of choice, with emphasis on complete removal to prevent recurrence. This case demonstrates successful excision with clear margins, preserving nasal structure and appearance. Long-term monitoring is essential for recurrence prevention. CONCLUSION: Isolated neurofibroma of the nasal tip is a rare condition in children. Surgical excision remains the treatment of choice, with careful planning required to preserve both cosmetic and functional outcomes. Regular follow-up is crucial to monitor for recurrence, especially in the absence of neurofibromatosis.
Authors: Abdullah Fadhel Almusallam, Mosab Tareq Atmeh, Mohammed Bader Obeidat, Hasan Zuhair El-Isa, Ahmed Smadi, Mousa Tarek Atmeh
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,800
OpenAlex ID: W4404893511