Binding of Perfluoroalkyl Substances to Nanoplastic Protein Corona Is pH‐Dependent and Attenuates Their Bioavailability and Toxicity
Year: 2024
Type: article
Abstract: Nanoplastics Nanoplastics serve as vectors for perfluoroalkyl pollutants in biological fluids, influencing protein binding behavior. Low pH weakens PFOS interactions while leaving PFOA unaffected, with PFOS still exhibiting greater serum persistence. Additionally, nanoplastics and serum albumin lower the cellular uptake and cytotoxicity of perfluoroalkyls by reducing their bioavailability. More in article number 2400255, Xingchen Zhao and co-workers.
Source: Small Science
Institutions: Qingdao University, Chinese Academy of Sciences, Qingdao Institute of Bioenergy and Bioprocess Technology, Hebei University, Shandong Normal University, Jianghan University, Shandong University, Goethe University Frankfurt, Fraunhofer Institute for Molecular Biology and Applied Ecology
Language: English
Subfield: Environmental Chemistry
Field: Environmental Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $5,770
OpenAlex ID: W4404899764
