Fatty Acid Metabolism Disruptions: A Subtle yet Critical Factor in Adverse Pregnancy Outcomes
Year: 2024
Type: article
Abstract: The establishment and maintenance of pregnancy encompass a series of complex and high-energy-consuming physiological processes, resulting in a significant energy demand. Fatty acids, one of the most essential nutrients, play a crucial role in energy supply via oxidation and perform critical biological functions such as anti-inflammatory and anti-oxidant effects, which substantially impact human health. Disordered fatty acid metabolism can cause anomalies in fetal growth and development, as well as a range of pregnancy problems, which can influence the health of both the mother and the fetus. In this review, we innovatively explore the relationship between fatty acid metabolism abnormalities and pregnancy complications, emphasizing the potential of dietary interventions with polyunsaturated fatty acids in improving pregnancy outcomes. These findings provide important evidence for clinical interventions and enhance the understanding and practical application of health management during pregnancy.
DOI: 10.7150/ijbs.103404
Authors: Xiao-Yan Cao, Meng-Ying Li, Chang-Xiang Shao, Jia-Lu Shi, Tao Zhang, Feng Xie, Ting Peng, Ming-Qing Li
Institutions: Shanghai Medical College of Fudan University, Shanghai Jiao Tong University, Fudan University, International Peace Maternity & Child Health Hospital, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Changning Maternity and Infant Health Hospital, East China Normal University, Chinese University of Hong Kong
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,337
OpenAlex ID: W4404929170