Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method
Year: 2024
Type: article
Abstract: Allylation of aldehydes was employed in combination with ring-closing metathesis (RCM) and oxidation reactions to achieve the synthesis of cyclic conjugated ketones. The synthetic strategy involved RCM of the mutual homoallylic alcohol intermediate followed by oxidation reaction to afford the six-membered cyclic enone. Moreover, when oxidation and RCM were completed successively, the five-membered cyclic enone was obtained.
Source: Results in Chemistry
Authors: Jorge Cruz-Huerta, Ericka Santacruz, Alejandro Castro, Jorge García-Dávila, Amado Grandes-Blanco
Institution: Universidad Autónoma de Tlaxcala
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,490
OpenAlex ID: W4404950000