Relationship of lung ultrasound score with oxygenation and pulmonary mechanics in mechanically ventilated patients: An observational study
Year: 2024
Type: article
Study design: Observational Study
Abstract: Background and Aims: Less than three B-lines indicate normal lung aeration, whereas multiple B-lines indicate moderate-to-severe loss of aeration. This study aimed to find a correlation between lung ultrasound score (LUSS) with oxygenation [ratio of arterial oxygen partial pressure (PaO 2 in mmHg) to fractional inspired oxygen (FiO 2 )] and respiratory mechanics (compliance and resistance). Methods: In total, 101 lung ultrasounds were performed in 50 patients aged 18–60 years, requiring mechanical ventilation for at least 24 hours. Twelve region methods was used, the number of B-lines were counted in each intercostal space, and LUSS was calculated. In addition, ventilator and arterial blood gas (ABG) parameters were noted. The correlation between these variables with LUSS was evaluated using Spearman’s coefficient. A receiver operating curve analysis was performed to find the cut-off value of LUSS to predict a PaO 2 /FiO 2 ratio of <200. Results: LUSS showed a negative correlation with PaO 2 /FiO 2 ratio (ρ = 0.827, P < 0.001) and lung compliance (ρ = 0.634, P < 0.001) but a positive linear correlation with lung resistance (ρ = 0.735, P < 0.001). LUSS > 12 predicts a PaO 2 /FiO 2 ratio of <200 with a specificity of 85.7% and a sensitivity of 97.37% ( P < 0.001). Conclusion: LUSS is an easy and effective bedside tool for measuring lung parameters in mechanically ventilated patients. It correlates moderately with oxygenation, lung compliance, and resistance.
Source: Indian Journal of Anaesthesia
Authors: Nishant Kumar, Ayushi Yadav, Maitree Pandey
Institution: Lady Hardinge Medical College
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404960619