Work

Breath-Holding as a Stimulus to Assess Peripheral Oxygenation Flow Using Near-Infrared Spectroscopic Imaging

Year: 2024

Type: article

Abstract: A mammalian breath-hold (BH) mechanism can induce vasoconstriction in the limbs, altering blood flow and oxygenation flow changes in a wound site. Our objective was to utilize a BH paradigm as a stimulus to induce peripheral tissue oxygenation changes via studies on control and diabetic foot ulcer (DFU) subjects. Subjects were imaged under a breath-hold paradigm (including 20 s BH) using a non-contact spatio-temporal-based NIRS device. Oxygenated flow changes were similar between darker and lighter skin colors but differed between wound site and normal background tissues. Thus, the ability of peripheral vasculature to response to oxygenation demand can be assessed in DFUs.

Source: Bioengineering

DOI: 10.3390/bioengineering11121221

Authors: Kevin Leiva, Isabella Gonzalez, Juan Murillo, Aliette Espinosa, Robert S. Kirsner, Anuradha Godavarty

Institutions: Florida International University, University of Miami

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,069