Development of squamous cell carcinoma at the bite sites several years following suspected cobra ( Naja naja ) envenomings
Year: 2024
Type: article
Study design: Case Report
Abstract: INTRODUCTION: Snakebite envenoming is a multidimensional issue that causes severe functional and life-challenging consequences among rural communities in tropical countries. Current research and treatments are largely focused on the acute effects of envenomation and short-term health outcomes. The knowledge of snakebite-induced long-term consequences is highly limited. CASE SERIES: ). Following bites, the victims presented typical symptoms of cobra envenomings including ptosis, altered sensorium, and breathing difficulties. However, difficult-to-heal wounds were a chronic health sequelae with frequent desquamation cycles which led to squamous cell carcinoma. Surgery as the primary therapeutic approach was used for all patients to address this issue. DISCUSSION: These patients highlight the importance of squamous cell carcinoma in previously damaged tissue from snakebites as a possible long-term consequence. This emphasises the need for surveillance systems focused on a broad range of snakebite-induced consequences including long-term pathological, psychological, and socioeconomic conditions. CONCLUSION: This case series describes pathological complications following cobra bites that require further research to determine mechanistic and epidemiological insights in the most affected regions by snakebites, specifically in India.
Source: Clinical Toxicology
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: hybrid
Funder: Medical Research Council
OpenAlex ID: W4404961345