Supplementary Figure S3 from TR-107, an Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells
Year: 2024
Type: supplementary-materials
Abstract: Supplementary Figure S3. Cell confluence images confirm a dose- and time-dependent inhibition of CRC cell proliferation. Colorectal cancer cells (A) LoVo, (B) NCI-H508, (C) LS 174T, and (D) RKO were treated in a 6-well plate format with vehicle control (0.1% DMSO) or indicated concentrations of TR-107 for 24, 48, and 72 hours. Phase-contrast live images (10× zoom) of cell confluence were captured at each time point. Images were processed with ImageJ and cell confluence was measured with PHANTAST 2.0 software as described in Materials and Methods. Data are presented as mean ± SD values (N=9). *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001.
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4404976321