Work

A versatile approach for geometry-based self-assembly of DNA–protein hybrid nanostructures using histone–DNA interactions

Year: 2024

Type: article

Abstract: We report an enhanced versatility in constructing DNA-protein hybrid nanostructures using histone-DNA complexes (HDs). By leveraging HDs, we demonstrate precise and scalable assembly of DNA origami tiles and a 2D triangular nanostructure. Our results extend the potential applications of DNA nanotechnology from the nanoscale to the microscale without the need for complex pre-designs.

Source: Chemical Communications

DOI: 10.1039/d4cc05253f

Authors: Hajar Al-Zarah, Maged F. Serag, Faisal Alkhaldi, Satoshi Habuchi

Institution: King Abdullah University of Science and Technology

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funder: King Abdullah University of Science and Technology

OpenAlex ID: W4404977282

FWCI: 0.47

Cites: 21

Cited by: 4

Related to: 10