Work

Stereodivergent assembly of δ-valerolactones with an azaarene-containing quaternary stereocenter enabled by Cu/Ru relay catalysis

Year: 2024

Type: article

Abstract: Stereodivergent synthesis of chiral δ-valerolactones bearing a unique azaarene-containing α-quaternary and a tertiary stereocenter was enabled by Cu/Ru relay catalysis via cascade borrowing hydrogen/Michael addition/lactonization protocol.

Source: Chemical Science

DOI: 10.1039/d4sc05852f

Authors: Kui Tian, Zhuan Jin, Xin-Lian Liu, Ling He, Hong-Fu Liu, Pin-Ke Yu, Xin Chang, Xiu-Qin Dong, Chun-Jiang Wang

Institutions: Wuhan University, Shanghai Institute of Organic Chemistry, State Key Laboratory of Organometallic Chemistry

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China

Awards: 基于双金属协同催化策略非蛋白质α-氨基酸衍生物的不对称合成研究, G6113403439, G6269267623, G6537439062, G7280560933, G7835802601, 基于非共价键次级作用协同活化策略发展新型手性双膦配体及其应用研究

OpenAlex ID: W4404977751

FWCI: 2.79

Cites: 87

Cited by: 20

Related to: 10