Work

Efficient development of high drug loaded posaconazole tablets enabled by amorphous solid dispersion

Year: 2024

Type: article

Abstract: A 50% API-loaded posaconazole tablet was developed in 14 days using just 1.5 g of API through systematic evaluation of stability, dissolution, and manufacturability.

Source: RSC Pharmaceutics

DOI: 10.1039/d4pm00301b

Authors: Tianyi Xiang, Sichen Song, Ronald A. Siegel, Changquan Calvin Sun

Institution: University of Minnesota

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Science Foundation, Division of Industrial Innovation and Partnerships

Awards: G3746148969, IUCRC Phase I UMN: Center for Integrated Material Science and Engineering of Pharmaceutical Products (CIMSEPP)

OpenAlex ID: W4404991206

FWCI: 1.476

Cites: 42

Cited by: 10

Related to: 10