Work

Unexpected RNA modification protects bacteria against viral infection

Year: 2024

Type: article

Abstract: Adding to the ever-growing list of newly discovered bacterial immune systems, we have characterized the mechanisms of an antiviral system called CmdTAC. CmdTAC blocks virus reproduction by modifying messenger RNA — a molecule needed to create proteins — through a chemical reaction not previously observed on an RNA base. A bacterial enzyme defends against phage infection by adding an ADP-ribose moiety to virus’s messenger RNA.

Source: Nature

DOI: 10.1038/d41586-024-03923-z

Language: English

Topic: Bacteriophages and microbial interactions

Subfield: Ecology

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $12,290

OpenAlex ID: W4404993342

FWCI:

Cites: 6

Cited by:

Related to: 10