Work

An amphiphilic peptide with unnatural amino acids as an alignment medium for RDC measurements

Year: 2024

Type: article

Abstract: with unnatural amino acids for the determination of anisotropic parameters of NMR is introduced. The amphiphilic peptide can be self-assembled at low concentrations in DMSO and is stable and highly homogeneous. The NMR spectrum collected with the addition of the medium had fewer background signals. The utility of the acquired RDC data is demonstrated to determine relative configuration of three natural products, Helminthosporic acid, Estrone, and α-Santonin.

Source: Magnetic Resonance Letters

DOI: 10.1016/j.mrl.2024.200171

Authors: Yishen Wang, Haizhi Yin, Yanling Yang, Zheng-Hui Li, Gao-Wei Li, Xinxiang Lei

Institutions: South Central Minzu University, Shangqiu Normal University, State Key Laboratory of Applied Organic Chemistry, Lanzhou University

Language: English

Topic: Molecular spectroscopy and chirality

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: National Natural Science Foundation of China, Henan Province Foundation for University Key Teacher, Science and Technology Program of Hunan Province, Science and Technology Program of Gansu Province

Awards: G1809228341, G2971947540, G5095756830, G7969227517, G8812944130