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Chemically Defined Organoid Culture System for Cholangiocyte Differentiation (Adv. Healthcare Mater. 30/2024)

Year: 2024

Type: article

Abstract: Cholangiocyte Organoids The jewelry box presents the chemically defined hydrogel (PIC) used for cholangiocyte organoid culture. The ring presents the PIC-cultured organoids; these organoids possess more mature cholangiocyte characteristics, such as bile acid (BA) homeostasis depicted on the box surface. Moreover, these mature cholangiocyte organoids effectively modeled the biliary pro-fibrotic response induced by TGFβ. This model is like a diamond ring that will shine on the path of scientific research and preclinical drug screening. More details can be found in article 2401511 by Rosalinde Masereeuw, Bart Spee, and co-workers.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.202470192

Authors: Zhenguo Wang, Shicheng Ye, Luc J.W. van der Laan, Kerstin Schneeberger, Rosalinde Masereeuw, Bart Spee

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4405000835

FWCI:

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