Work

Results of the 2023 rapid DNA multi-laboratory study – I-Chip

Year: 2024

Type: article

Abstract: Identical sensitivity and mixture sample sets were provided to six external laboratories to evaluate the recent enhancements to the Rapid DNA technology for crime scene-type samples. Data were returned to the Federal Bureau of Investigation and the National Institute of Standards and Technology for review and analysis. Manual interpretation (modified Rapid DNA analysis) was conducted on all samples to assess the success of genotyping for both full profiles and the 20 Combined DNA Index System (CODIS) core STR loci using 18 total cellular DNA input amounts ranging from 102.4 ng to 0.025 ng. Two-person and three-person mixtures at varying ratios for two total DNA inputs were analyzed and observed allele percentages were compared to expected allele percentages.

Source: Forensic Science International Reports

DOI: 10.1016/j.fsir.2024.100395

Authors: Erica L. Romsos, Lilliana I. Moreno, Douglas R. Hares

Institutions: National Institute of Standards and Technology, Federal Bureau of Investigation

Language: English

Topic: Forensic and Genetic Research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $870

Funders: U.S. Department of Justice, National Institute of Standards and Technology, Office of Justice Programs, National Institute of Justice