Work

Infiltrative Myocardial T-Cell Lymphoma

Year: 2024

Type: article

Abstract: We report a unique case involving cardiac manifestation of T-cell lymphoma and associated risk management of ventricular arrhythmia and sudden cardiac death. A 39-year-old woman presented with a syndrome consistent with fever in a returned traveler, ultimately diagnosed with stage IV peripheral T-cell lymphoma involving the myocardium with ventricular tachycardia. Management of risk of sudden cardiac death was complicated by hematological management with an antibody-drug conjugate chemotherapy regimen and later autologous stem cell transplant. There was no significant evidence base to consult for management of the present case. Management proceeded on careful multidisciplinary team discussion, risk assessment extrapolated from cardiac sarcoidosis, and consideration of a vulnerable and previously health young patient.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2024.102831

Authors: Alexander Podgorski, Daniel Tardo, Callum Cherrett, Orly Lavee, Jason C. Kovacic

Institutions: St Vincent's Hospital Sydney, Victor Chang Cardiac Research Institute, The University of Notre Dame Australia, UNSW Sydney, Icahn School of Medicine at Mount Sinai

Language: English

Topic: Cardiac tumors and thrombi

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850