Work

Case Report and Literature Review of “Treatment Failure” of Aspergillus Infection Secondary to Influenza a Virus

Year: 2024

Type: article

Abstract: Purpose: Increased clinical manifestations combined with increased lung imaging findings during antifungal therapy are often misjudged as failure of antifungal therapy, and should be vigilant against immune reconstitution inflammatory syndrome. Case: We describes a case of invasive pulmonary Aspergillus infection after Influenza A Virus (IAV). After active antifungal therapy, the patient's clinical symptoms continued to worsen, imaging lesions continued to progress, laboratory indicators improved, and immune reconstitution inflammatory syndrome was considered. Conclusion: The clinical characteristics and treatment process of this case were summarized, and related literature search was carried out, in order to provide a new perspective for the treatment failure of fungal infection in the future, and to avoid the random change of antifungal drugs, which may lead to the increase of drug resistance.

Source: Journal of Inflammation Research

DOI: 10.2147/jir.s496441

Authors: Peikun Teng, Yuzhan Liu, Xingyu Zhang, Nianxu Luan, Xiudi Han, Xuedong Liu

Institutions: Qingdao Municipal Hospital, University of Health and Rehabilitation Sciences

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,836