Comparative Anti-Anaemia Efficacy of Jatropha tanjorensis and Telfairia occidentalis Leaf Extracts in Aluminium Chloride (AlCl₃) Induced -Anaemia in Albino Rats
Year: 2024
Type: article
Abstract: Anaemia is a blood illness that threatens public health. The anti-anaemia property of Jatropha tanjorensis and Telfairia occidentalis is known. However, information on their respective measures of anti-anaemia potential is veiled. Comparing the anti-anaemia potential of extracts from the said plants is pivoted in this investigation. J. tanjorensis (JTLE) and T. occidentalis (TOLE) leaves were ground into a fine powder and then macerated. Twenty-one (21) mature male albino rats were divided into seven groups of three (3) rats per group. Anaemia was induced in groups IIVII, after which extracts were administered orally for 21 consecutive days. Group I (normal control) and Group II were not administered extract. The third and fourth groups received 200 mg/kg of T. occidentalis and J. tanjorensis leaf extract, respectively. Groups V and VI received 400 mg/kg of T. occidentalis and J. tanjorensis leaf extracts, respectively. Group VII received extract composite (1:1). Standard techniques were used to evaluate the major anaemia indices. Findings regarding the relative anti-anaemia effectiveness of J. tanjorensis and T. occidentalis leaf extracts revealed that the extracts did not prevent the treated animals' body weight from increasing. Additionally, 200 mg/kg of the composite extract was found to significantly (p< 0.05) raise blood parameters above those reported for their respective components. PCV value recorded with 400 mg/kg bw of TOLE was considerably (p < 0.05) greater than that reported for JTLE. In conclusion, T. occidentalis had a better anti-anaemia potential.
Authors: Ephraim Madu, John Wassagwa, Ewa Ogbonnaya, Oluwafemi A. Adepoju, Melford U. Elendu, Victor C. Amoke
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4405019868