Work

Endothelial cell Ass1 inhibits arteriosclerotic calcification in diabetes mellitus

Year: 2024

Type: article

Abstract: mouse aorta after adeno-associated virus intervention. It was found that the differential protein Ptk2b was closely related to vascular calcification (VC) and interacted with the target protein Ass1. The above studies indicate that endothelial Ass1 affects calcification formation in diabetic plaques, and the mechanism may be related to Ptk2b. Ass1 may be a new target for the treatment of diabetic VC.

Source: Biomedicine & Pharmacotherapy

DOI: 10.1016/j.biopha.2024.117739

Authors: Han Jiang, Ye Zhou, Lili Zhang, Wenhua Yu, Lihua Li, Zhiyin Dai, Li Zhao, Zhongqun Wang

Institutions: Jiangsu University, Affiliated Hospital of Jiangsu University

Language: English

Topic: Dermatological and Skeletal Disorders

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,420

Funders: Project on Maternal and Child Health Talents of Jiangsu Province, Jiangsu Commission of Health, National Natural Science Foundation of China, Jiangsu University

Awards: G1124521263, G3259047820, G3725746617, G619721123, G7688833083

OpenAlex ID: W4405060980

FWCI: 1.201

Cites: 36

Cited by: 5

Related to: 10