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Utilizing Alkyne‐Nitrone Cycloaddition for the Convenient Multi‐Component Assembly of Protein Degraders and Biological Probes

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Year: 2024
Type: article
Source: Chemistry - A European Journal
DOI: 10.1002/chem.202403184
Authors: Shiou‐Ting Lin, Chien‐Hua Wang, Ai‐Lin Chen, Tsung‐Shing Andrew Wang
Institution: National Taiwan University
Language: English

Topic: Protein Degradation and Inhibitors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: closed

Funders: National Science and Technology Council, National Taiwan University, Center for Emerging Material and Advanced Devices, National Taiwan University
Awards: G1602016021, G2430723732, G3897461137, G5917197107, G6214349549, G6226305502, G6485499503, G6552968651, G7756292109, Develop a Photoactivatable and Real-Time Trackable Tubulin-Targeting Small-Molecule Toolkit( I ), Development of Aqueous Compatible Conjugation Reactions and Their Applications in Targeted Covalent Inhibitors, Proteolysis Targeting Chimeras and Metabolomic Probes
OpenAlex ID: W4405106141
FWCI: 0.461
Cites: 66
Cited by: 4
Related to: 10
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