Progress in the study of metastatic mechanism of colorectal cancer in vivo
Year: 2024
Type: article
Abstract: The main object of this paper is colorectal cancer (CRC). Colorectal cancer is a malignant tumor that occurs in the colon or rectum. It is one of the most common cancers in the digestive system in the world. Its pathogenesis is complex and is related to many factors, including genetic factors and lifestyle habits. Mild cases can be treated and have a high probability of recovery, but severe tumors can even be fatal. For CRC, this paper includes its pathogenesis, metastasis mechanism, and corresponding intervention measures. Through research on these aspects, it aims to have a more comprehensive understanding of the causes, development process, and treatment strategies of CRC. The pathogenesis of CRC is usually affected by many different factors. This article will mainly discuss the factors of genetics, diet, and lifestyle. In terms of metastasis mechanism, tumor immune microenvironment, epithelial-mesenchymal transition (EMT), and vascular growth factors play a decisive and key role. Then this article also discusses intervention measures for CRC, including inhibiting the formation of new blood vessels, immunotherapy, and the use of chemotherapy agents.
Source: Theoretical and Natural Science
Author: Wanqing Li
Institution: University of Washington
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4405116117