Work

Clinical, antibiotic resistance features, and treatment outcomes of Vietnamese patients with community-acquired sepsis caused by Klebsiella pneumoniae

Year: 2024

Type: article

Abstract: Objectives: septicemia acquired in the Vietnamese community. Methods: from July 2018 to July 2023. Results: strains were resistant to cephalosporins and quinolones (8-10%) and ampicillin (87%). Late hospitalization raises the risk of mortality by ∼3.5 times, and combination therapy with more than two kinds of antibiotics increases the risk of death by ∼1.8 times. The mortality rates were 9.1% and 63.6% after 4-6 and 2-3 weeks of therapy, respectively. Of the 11 patients who died, 90.9% died of septic shock, whereas 9.1% died of sepsis. Conclusions: resistance to ampicillin. Organ dysfunction and late hospitalization were associated with septic shock and death.

Source: IJID Regions

DOI: 10.1016/j.ijregi.2024.100505

Authors: Tran Van Giang, Nguyen Kim Anh, Nguyen Quoc Phuong, Le Thanh Dat, Le Van Duyet

Institutions: Hanoi Medical University, Hospital for Tropical Diseases

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,200