Association of Polymorphism in Locus of rs274503 ( ZBED5 / GALNT18 ) with the Risk of Idiopathic Clubfoot in Chinese Children: An 11-Center Case–Control Study
Year: 2024
Type: article
Study design: Observational Study
Abstract: Idiopathic clubfoot (IC) can be corrected initially using the Ponseti method, but still there is a high recurrence rate. The etiology of IC may include many undetermined genetic and environmental factors. Single nucleotide polymorphism of rs274503 in ZBED5/GALNT18 has been found to be associated with IC in Caucasian children. Therefore, we decided to investigate the association between this polymorphism and the risk of IC in the Chinese population.
Institutions: Guangzhou Women and Children Medical Center, Wuhan Union Hospital, Huazhong University of Science and Technology, Southern Medical University, Guangzhou Medical University, Kunming Children's Hospital, Hunan Children's Hospital, Shenzhen Children's Hospital, Xiamen University, Fuzhou Second Hospital, Foshan Hospital of TCM, Wuhan Medical Center for Women and Children, Tongji Hospital, Dalian Medical University, Children's Hospital of Chongqing Medical University, Chongqing Medical University
Language: English
Topic: Foot and Ankle Surgery
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4405185155