Work

Intense fibroblast activation protein inhibitor localization around the site of embolized gastroduodenal artery in a patient with metachronous pancreatic adenocarcinoma: A potential pitfall in positron imaging

Year: 2024

Type: article

Abstract: 68 Gallium-Fibroblast activation protein inhibitor ( 68 Ga-FAPI) positron emission tomography/computed tomography (PET/CT) is increasingly used for evaluating various epithelial neoplasms. Despite addressing some pitfalls, many remain unacknowledged. This report details a 77-year-old man with suspected pancreatic malignancy who underwent a 68 Ga-FAPI PET/CT scan post-gastroduodenal coil embolization for upper gastrointestinal bleeding. The scan revealed intense 68 Ga-FAPI uptake in the pancreatic body and tail malignancy and around the embolized gastroduodenal artery, indicating a healing process. This highlights the importance of understanding FAPI expression in recent surgical sites for accurate radiologic interpretation.

Source: Acta Radiologica Open

DOI: 10.1177/20584601241307350

Authors: Ahmed Saad Abdlkadir, Hasan Alalawi, Akram Al-Ibraheem

Institutions: King Hussein Cancer Center, University of Jordan

Language: English

Topic: Peptidase Inhibition and Analysis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,023