Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder

Year: 2024

Type: article

Abstract: T1-weighted MRI and resting-state functional MRI revealed structural and functional brain alterations in opioid receptor–dense regions, such as the thalamus, right medial temporal lobe, cerebellum, and brainstem, in individuals with opioid use disorder compared with healthy controls.

Source: Radiology

DOI: 10.1148/radiol.240514

Institutions: Yale University, Vanderbilt University, Roger Williams Medical Center, Quinnipiac University, Brigham and Women's Hospital, APT Foundation, University of Connecticut, VA Connecticut Healthcare System

Language: English

Topic: Functional Brain Connectivity Studies

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute of General Medical Sciences, National Center for Advancing Translational Sciences

Awards: G1044130170, G1796354790, G3553504618, G6103062288, Medical Scientist Training Program, G846228670, G9000033035, G9000066276, G9000093551, Yale Clinical and Translational Science Award, J. NRSA Training Core

OpenAlex ID: W4405205620